Table S3. Correlation between expression levels of 9 abnormally expressed lncRNAs and clinical characteristics of NPSLE patients.
Clinical characteristics | r vs. P | NONHSAT208182.1 | NONHSAT001281.2 | NONHSAT024353.2 | NONHSAT182114.1 | NONHSAT106801.2 | NONHSAT039491.2 | ENST00000356215 | NONHSAT087499.2 | NONHSAT207026.1 |
---|---|---|---|---|---|---|---|---|---|---|
SLEDAI | r | –0.17 | –0.09 | –0.28 | –0.07 | –0.36 | –0.44 | 0.09 | 0.09 | 0.30 |
P | 0.40 | 0.65 | 0.16 | 0.72 | 0.07 | 0.02 | 0.66 | 0.67 | 0.14 | |
Age | r | –0.001 | –0.22 | –0.20 | 0.04 | –0.03 | 0.15 | –0.19 | –0.11 | –0.12 |
P | 0.99 | 0.27 | 0.32 | 0.86 | 0.89 | 0.47 | 0.35 | 0.58 | 0.56 | |
Duration of disease | r | 0.24 | 0.26 | 0.01 | 0.02 | 0.07 | 0.35 | 0.08 | –0.07 | –0.23 |
P | 0.23 | 0.20 | 0.98 | 0.91 | 0.73 | 0.08 | 0.69 | 0.73 | 0.26 | |
Olfactory threshold | r | –0.25 | –0.35 | 0.23 | –0.33 | –0.21 | 0.43 | –0.64 | –0.16 | 0.09 |
P | 0.49 | 0.32 | 0.52 | 0.35 | 0.57 | 0.22 | 0.05 | 0.66 | 0.81 | |
Olfactory memory | r | 0.13 | –0.68 | –0.27 | 0.07 | –0.53 | –0.75 | –0.20 | –0.23 | 0.04 |
P | 0.73 | 0.03 | 0.44 | 0.86 | 0.11 | 0.01 | 0.58 | 0.52 | 0.92 | |
WBC (CSF) | r | –0.07 | 0.15 | –0.56 | –0.33 | –0.16 | 0.26 | –0.25 | –0.36 | 0.17 |
P | 0.82 | 0.63 | 0.06 | 0.29 | 0.62 | 0.42 | 0.43 | 0.26 | 0.60 | |
Protein (CSF) | r | 0.18 | –0.14 | –0.40 | 0.50 | –0.03 | –0.07 | –0.09 | 0.18 | –0.34 |
P | 0.58 | 0.65 | 0.20 | 0.10 | 0.92 | 0.82 | 0.78 | 0.58 | 0.28 | |
Albumin (CSF) | r | 0.36 | 0.08 | –0.36 | 0.50 | 0.29 | 0.01 | 0.04 | 0.28 | –0.39 |
P | 0.28 | 0.81 | 0.28 | 0.12 | 0.38 | 0.98 | 0.90 | 0.41 | 0.24 | |
IgG (CSF) | r | 0.01 | –0.22 | –0.36 | 0.39 | –0.26 | –0.21 | –0.10 | 0.03 | –0.39 |
P | 0.99 | 0.51 | 0.28 | 0.24 | 0.44 | 0.54 | 0.76 | 0.93 | 0.24 | |
C3 | r | –0.02 | 0.02 | 0.08 | –0.11 | 0.11 | 0.24 | –0.25 | –0.09 | –0.14 |
P | 0.93 | 0.92 | 0.70 | 0.62 | 0.61 | 0.26 | 0.25 | 0.66 | 0.52 | |
C4 | r | –0.18 | –0.04 | 0.20 | 0.02 | –0.11 | 0.10 | –0.25 | –0.10 | –0.16 |
P | 0.41 | 0.84 | 0.34 | 0.93 | 0.60 | 0.64 | 0.24 | 0.64 | 0.46 | |
Globulin | r | –0.08 | –0.21 | –0.39 | 0.02 | –0.10 | –0.14 | –0.23 | 0.03 | –0.04 |
P | 0.70 | 0.29 | 0.05 | 0.92 | 0.64 | 0.49 | 0.25 | 0.87 | 0.86 | |
Albumin | r | 0.09 | 0.26 | 0.22 | –0.20 | 0.29 | 0.38 | 0.06 | –0.16 | –0.02 |
P | 0.67 | 0.20 | 0.27 | 0.32 | 0.15 | 0.05 | 0.77 | 0.45 | 0.91 | |
IgG | r | 0.01 | –0.33 | –0.41 | 0.11 | –0.18 | –0.10 | –0.17 | –0.14 | –0.12 |
P | 0.96 | 0.11 | 0.04 | 0.60 | 0.38 | 0.64 | 0.40 | 0.50 | 0.57 | |
IgA | r | –0.13 | 0.08 | –0.14 | 0.0008 | –0.03 | –0.08 | –0.20 | 0.26 | 0.07 |
P | 0.52 | 0.71 | 0.51 | 1.00 | 0.90 | 0.69 | 0.34 | 0.20 | 0.75 | |
IgM | r | –0.18 | 0.05 | 0.01 | –0.29 | –0.07 | 0.10 | –0.15 | 0.17 | 0.18 |
P | 0.40 | 0.82 | 0.98 | 0.17 | 0.74 | 0.63 | 0.47 | 0.42 | 0.39 | |
IgE | r | –0.18 | –0.40 | –0.26 | 0.24 | –0.03 | –0.02 | –0.04 | 0.04 | 0.03 |
P | 0.40 | 0.05 | 0.21 | 0.24 | 0.87 | 0.91 | 0.86 | 0.85 | 0.88 | |
24 h proteinuria | r | 0.22 | –0.19 | –0.37 | –0.02 | –0.28 | –0.30 | 0.10 | 0.11 | 0.40 |
P | 0.31 | 0.37 | 0.08 | 0.93 | 0.19 | 0.17 | 0.65 | 0.61 | 0.06 | |
Cr | r | 0.03 | 0.17 | 0.19 | –0.05 | –0.15 | –0.26 | 0.12 | 0.09 | 0.23 |
P | 0.90 | 0.41 | 0.36 | 0.79 | 0.47 | 0.20 | 0.55 | 0.68 | 0.26 | |
BUN | r | 0.09 | –0.30 | –0.08 | –0.04 | –0.18 | –0.11 | –0.07 | –0.11 | –0.09 |
P | 0.68 | 0.13 | 0.71 | 0.85 | 0.37 | 0.58 | 0.72 | 0.58 | 0.66 | |
UA | r | 0.06 | 0.09 | 0.15 | –0.11 | –0.20 | –0.21 | 0.12 | 0.12 | 0.46 |
P | 0.79 | 0.65 | 0.47 | 0.60 | 0.33 | 0.29 | 0.54 | 0.57 | 0.02 | |
GFR | r | –0.03 | –0.18 | –0.02 | –0.08 | 0.19 | 0.15 | –0.30 | –0.14 | –0.45 |
P | 0.90 | 0.37 | 0.94 | 0.71 | 0.35 | 0.46 | 0.14 | 0.48 | 0.02 | |
CRP | r | –0.32 | –0.20 | –0.12 | –0.06 | –0.35 | –0.004 | –0.16 | –0.13 | –0.18 |
P | 0.11 | 0.32 | 0.55 | 0.78 | 0.08 | 0.99 | 0.43 | 0.52 | 0.38 | |
ESR | r | –0.24 | –0.32 | –0.20 | –0.17 | –0.30 | –0.27 | –0.28 | 0.10 | 0.09 |
P | 0.26 | 0.12 | 0.35 | 0.41 | 0.15 | 0.19 | 0.18 | 0.63 | 0.66 | |
WBC | r | –0.09 | 0.29 | –0.05 | –0.14 | –0.11 | 0.07 | 0.11 | –0.21 | –0.09 |
P | 0.68 | 0.15 | 0.83 | 0.49 | 0.61 | 0.74 | 0.60 | 0.31 | 0.67 | |
HB | r | 0.03 | 0.21 | 0.35 | –0.15 | 0.22 | 0.38 | –0.19 | –0.04 | –0.02 |
P | 0.89 | 0.31 | 0.08 | 0.46 | 0.28 | 0.05 | 0.35 | 0.85 | 0.91 | |
PLT | r | –0.10 | 0.25 | –0.16 | –0.02 | –0.08 | 0.04 | –0.05 | 0.07 | 0.31 |
P | 0.61 | 0.23 | 0.43 | 0.92 | 0.69 | 0.86 | 0.80 | 0.73 | 0.12 | |
Urinary RBC | r | 0.72 | 0.26 | –0.32 | 0.24 | 0.30 | –0.04 | 0.17 | 0.35 | –0.10 |
P | <0.0001 | 0.19 | 0.11 | 0.23 | 0.14 | 0.85 | 0.41 | 0.08 | 0.63 | |
D-Dmier | r | 0.17 | 0.08 | 0.0008 | –0.16 | –0.09 | 0.05 | –0.23 | –0.19 | –0.14 |
P | 0.45 | 0.73 | 1.00 | 0.47 | 0.69 | 0.83 | 0.30 | 0.39 | 0.53 | |
CD4+ T cells | r | –0.60 | 0.18 | 0.28 | –0.24 | –0.14 | 0.08 | –0.51 | 0.05 | –0.03 |
P | 0.12 | 0.67 | 0.50 | 0.56 | 0.74 | 0.84 | 0.20 | 0.90 | 0.94 | |
CD8+ T cells | r | –0.55 | 0.08 | 0.27 | 0.29 | 0.06 | 0.36 | 0.03 | –0.03 | –0.16 |
P | 0.15 | 0.84 | 0.52 | 0.48 | 0.89 | 0.38 | 0.95 | 0.94 | 0.71 | |
NK cells | r | 0.11 | 0.36 | 0.35 | 0.05 | 0.41 | 0.58 | –0.05 | –0.26 | 0.002 |
P | 0.79 | 0.38 | 0.40 | 0.90 | 0.31 | 0.13 | 0.91 | 0.53 | 1.00 | |
B cells | r | –0.44 | –0.31 | –0.58 | 0.04 | –0.83 | –0.00008 | –0.45 | –0.04 | –0.01 |
P | 0.79 | 0.38 | 0.40 | 0.90 | 0.31 | 0.13 | 0.91 | 0.53 | 1.00 | |
PAH | r | –0.58 | –0.41 | 0.60 | –0.41 | –0.55 | –0.08 | –0.62 | –0.52 | –0.46 |
P | 0.04 | 0.16 | 0.03 | 0.17 | 0.05 | 0.80 | 0.02 | 0.07 | 0.12 | |
CFH | r | –0.10 | 0.08 | 0.31 | –0.32 | –0.03 | –0.50 | 0.43 | 0.21 | 0.03 |
P | 0.24 | 0.45 | 0.14 | 0.21 | 0.13 | 0.12 | 0.08 | 0.13 | 0.90 | |
P2RY14 | r | –0.34 | 0.23 | 0.32 | 0.34 | –0.34 | –0.38 | 0.42 | –0.06 | –0.32 |
P | 0.24 | 0.34 | 0.35 | 0.12 | 0.09 | 0.34 | 0.23 | 0.92 | 0.13 | |
VNN1 | r | 0.34 | 0.24 | 0.03 | 0.08 | 0.23 | 0.53 | –0.23 | –0.024 | 0.03 |
P | 0.22 | 0.25 | 0.48 | 0.83 | 0.32 | 0.39 | 0.07 | 0.98 | 0.83 | |
IDO1 | r | –0.61 | –0.09 | –0.28 | 0.08 | –0.43 | 0.09 | 0.32 | –0.05 | –0.54 |
P | 0.02 | 0.19 | 0.32 | 0.92 | 0.09 | 0.84 | 0.34 | 0.67 | 0.09 | |
BCL2A1 | r | 0.45 | 0.38 | 0.42 | 0.37 | –0.33 | 0.93 | –0.92 | –0.43 | –0.42 |
P | 0.03 | 0.05 | 0.32 | 0.22 | 0.06 | 0.10 | 0.35 | 0.93 | 0.23 | |
KCNJ15 | r | –0.34 | 0.54 | 0.23 | –0.84 | –0.03 | 0.23 | –0.33 | 0.45 | –0.32 |
P | 0.50 | 0.14 | 0.06 | 0.32 | 0.94 | 0.24 | 0.09 | 0.34 | 0.32 |
The r and P values of nonparametric analysis are listed. SLEDAI, SLE disease activity index; yrs, years; NPSLE, neuropsychiatric systemic lupus erythematosus; WBC (CSF), white blood cells in cerebrospinal fluid; Protein (CSF), protein in cerebrospinal fluid; Albumin (CSF), albumin in cerebrospinal fluid; IgG (CSF), immunoglobulin G in cerebrospinal fluid; C3, complement 3; C4, complement 4; IgG, immunoglobulin G; IgA, immunoglobulin A; IgM, immunoglobulin M; IgE, immunoglobulin E; 24 h proteinuria, 24 hour proteinuria; Cr, creatinine; BUN, urea nitrogen; UA, uric acid; GFR, glomerular filtration rate; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; WBC, white blood cells; HB, hemoglobin; PLT, platelet; Urinary RBC, urinary red blood cells; NK cells, natural killer cell; PAH, pulmonary hypertension; CFH, complement factor H; P2RY14, purinergic receptor P2Y14; VNN1, vanin 1; IDO1, Indoleamine 2,3-dioxygenase 1; BCL2A1, BCL2 related protein A1; KCNJ15, Potassium voltage-gated channel subfamily J member 15.