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. 2020 Mar;8(6):327. doi: 10.21037/atm.2020.02.107

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2020 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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Morusin inhibits human renal cell carcinoma growth in vivo. (A) Xenograft tumor volume growth during the treatment period. (B) Volume difference in negative control and treatment group. (C) Tumor morphology in the treatment group (down) and negative control (up). (D) Tumor weight increased after 21 days of treatment. (E) Tumor immunohistochemical analysis for Ki-67 and P27. *, P<0.05, **, P<0.01, and ***, P<0.001 compared to negative control. (F) P38, JNK, and ERK induced by morusin in mice tumor. Every group has three repetition.