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. 2020 Mar;8(6):356. doi: 10.21037/atm.2020.02.57

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2020 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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Effects of estrogen deprivation on the time spent in the dark chamber (A) and the number of errors (B) in the STPA test. One-way ANOVA and a post hoc LSD test were conducted. Data are presented as the mean ± SEM. n=14–15 for each group. *, P<0.05 means significant difference between the OVX and Sham groups; **, P<0.01 means significant difference between the OVX and Sham groups. OVX group, ovariectomized group; Sham group, sham-operated group; STPA, step-through passive avoidance; SEM, standard error of the mean.