Table 3. Co-occurrence or mutual exclusive alterations of NAT1 and its co-expression genes.

Gene A	Gene B	P value	Log odds ratio	Association
NAT1	SCUBE2	<0.001	1.160	Tendency towards co-occurrence
NAT1	GATA3	0.069	0.411	Tendency towards co-occurrence
NAT1	FOXA1	0.273	0.287	Tendency towards co-occurrence
NAT1	GPR160	0.549	−0.036	Tendency towards mutual exclusivity
NAT1	TFF3	0.592	−0.030	Tendency towards mutual exclusivity

The query contains 2 gene pairs with mutually exclusive alterations (all significant), and 3 gene pairs with co-occurrent alterations (1 significant). Log odds ratio >0: association towards co-occurrence; log odds ratio ≤0: association towards mutual exclusivity; P value <0.05: significant association; P value: derived from Fisher exact test; log odds ratio: quantifies how strongly the presence or absence of alterations in gene A are associated with the presence or absence of alterations in gene B in the selected tumors.