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. 2020 Mar;8(6):388. doi: 10.21037/atm.2020.03.120

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2020 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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A 48-year-old man with hepatocellular carcinoma (HCC) in the VI segment of the liver. A low-density lesion in the right lobe of the liver 2.7 cm in size on normal abdominal CT images (A) with nonuniform hyperenhancement (not rim) in the arterial phase (B) and “washout” appearance in the portal venous phase (C); after radiofrequency ablation (RFA), a non-enhanced ablation area was shown (D), but with no nodular or irregular enhancement except for an nonsmoothed rim (arrows) of enhancement on arterial (E) and portal venous phases (F). There was inconsistent diagnosis between the 2 readers (R1: equivocal; R2: nonviable. The final conclusion re-valuated by R3: equivocal).