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. 2020 Mar;8(6):386. doi: 10.21037/atm.2020.03.121

Table 2. Positive results of different laboratory tests in 164 children of different ages infected with MP infection confirmed by BALF PCR.

Parameters ≤1-year-old (n=23) 1–3 years old (n=23) 3–5 years old (n=52) >5 years old (n=66) P value
IgM [n (%)] 5 (21.74) 17 (73.91)a 36 (69.23)a 47 (71.21)a <0.001
Paired IgG [n (%)] 9 (39.13) 12 (52.17) 30 (57.69) 38 (57.58) 0.440
NPA PCR [n (%)] 7 (30.43) 15 (65.22) 30 (57.69) 48 (72.72)a 0.004
Combinated IgM and NPA PCR test [n (%)] 9 (39.13) 18 (78.26) 41 (78.85)a 56 (84.85)a,e <0.001
P value 0.537 0.245 0.064 0.007

Positive results of the same diagnostic test indifferent age groups were compared. a, P<0.05 compared with patients ≤1-year-old. Positive results of different diagnostic tests in the same age group were compared. e, P<0.05 compared with the diagnostic teste of paired IgG. MP, Mycoplasma pneumoniae; BALF, bronchoalveolar lavage fluid; PCR, polymerase chain reaction; IgM, immunoglobulin M; IgG, immunoglobulin G; NPA, nasopharyngeal aspirate.