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. 2020 Mar;8(6):378. doi: 10.21037/atm.2020.02.14

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2020 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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IGSF3 enhances HCC cell migration and invasion in vitro. (A,B) Cell migration capability of HCLLM3 and hepG2 cells transfected with either shIGSF3 or shCON as assessed by transwell migration (left panel). Bar graph shows data representing relative number of migration cells in each field; (C,D) cell invasion capability of cells with shIGSF3 or shCON as assessed by transwell migration (left panel). Bar graph shows data representing relative number of migration cells in each field; (E,F) wound healing assays of HCLLM3 and hepG2 with IGSF3 knockdown. All experiments were performed three times. Results were represented as mean ± SD (*, P<0.05; **, P<0.01; ***, P<0.001).