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. 2020 Mar;8(6):350. doi: 10.21037/atm.2020.02.103

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2020 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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Differential osteoblastic and osteoclastic activities in ipsilateral and contralateral knees after ACLT. Representative photos of TRAP staining (A) and Osterix immunostaining (B) in ipsilateral and contralateral tibial subchondral bone in different time points after ACLT. statistical analysis of TRAP staining (C) and Osterix immunostaining (D), n=8 per group, statistical significance was determined by unpaired Student’s t test and all data were shown as a bar with means ± standard deviations. Scale bar, 20 µm; *, P<0.05, **, P<0.01, ***, P<0.001 compared with the sham operated group at different time points. ACLT, anterior cruciate ligament transection.