. 2020 Apr 27;3(4):e203394. doi: 10.1001/jamanetworkopen.2020.3394

Table. One-Day Change in PC, CT-ADP, and NeoBAT Score by Type of Transfusion in Infants With Gestational Age Less Than 27 Weeks.

Outcome	Infants receiving transfusion^a			Infants not receiving transfusion^a			P value^b
Outcome	Sample pairs	Mean (SE)	P value	Sample pairs	Mean (SE)	P value	P value^b
Platelet transfusion
Change in PC, ×10³/μL	21	31 (9)	.002	55	11 (6)	.06	.06
Change in CT-ADP, s	20	–51 (22)	.03	47	–11 (14)	.44	.14
Change in bleeding score
All infants	29	–0.28 (0.18)	.12	79	–0.11 (0.11)	.29	.44
Infants with ≥2 bleeding score on first day	13	–0.54 (0.32)	.12	23	–0.65 (0.24)	.02	.78
Fresh frozen plasma transfusion
Change in CT-ADP, s	9	–10 (33)	.76	58	–25 (13)	.06	.68
Change in bleeding score
All infants	11	–0.27 (0.29)	.35	97	–0.14 (0.10)	.14	.67
Infants with ≥2 bleeding score on first day	6	–0.17 (0.47)	.73	30	–0.70 (0.21)	.005	.32
Erythrocyte transfusion
Change in hematocrit, %	28	–0.6 (1.0)	.56	44	–1.3 (0.8)	.14	.63
Change in CT-ADP, s	27	–23 (19)	.23	40	–23 (15)	.16	.98
Change in bleeding score
All infants	31	–0.26 (0.17)	.14	77	–0.12 (0.11)	.29	.49
Infants with ≥2 bleeding score on first day	9	–1.00 (0.38)	.02	27	–0.48 (0.22)	.05	.26

Abbreviations: CT-ADP, closure time in response to adenosine diphosphate; NeoBAT, Neonatal Bleeding Assessment Tool; PC, platelet count.

SI conversion factors: To convert hematocrit to proportion of 1.0, multiply by 0.01; PC to ×10⁹/L, multiply by 1.0.

^{^a}

Mean (SE) 1-day change was adjusted for within-patient correlation. P tests for mean change of 0.

^{^b}

Comparing mean change on days with or without transfusions.