TABLE 3.
Cox regression model for time to primary outcome of death, VAD placement, or transplant
| Unadjusted | Adjusteda | |||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P-value | HR | 95% CI | P-value | |
| Septum TDI-MPI z-score | ||||||
| ≥2 | 2.13 | 1.12–4.04 | .02 | 2.31 | 1.13–4.74 | .02 |
| <2 | ref | - | - | ref | - | - |
| LV shortening fraction | 0.91 | 0.86–0.96 | <.01 | 0.91 | 0.86–0.98 | <.01 |
| LVEDD z-score | 1.07 | 0.99–1.17 | .09 | 1.06 | 0.95–1.218 | .29 |
| Mitral regurgitation | ||||||
| Severe | 2.83 | 1.09–7.30 | .03 | 1.16 | 0.35–3.90 | .81 |
| Moderate | 1.58 | 0.59–4.25 | .36 | 0.81 | 0.27–2.46 | .71 |
| Mild | 1.75 | 0.72–4.26 | .22 | 0.77 | 0.25–2.31 | .77 |
| None | ref | - | - | ref | - | - |
| Peak TR gradient | 1.01 | 0.99–1.03 | .21 | - | - | - |
| Peak TR gradient as % of systolic blood pressure | 1.87 | 0.44–8.02 | .40 | - | - | - |
| On milrinoneat time of echo | 2.32 | 1.24–4.36 | .01 | 1.61 | 0.75 −3.49 | .22 |
| Age at presentation | ||||||
| ≥2 y | 1.22 | 0.67–2.22 | .53 | - | - | - |
| <2 y | ref | - | - | - | - | |
| Initial BNP | 1.01 | 0.99–1.01 | .16 | - | - | - |
Abbreviations: BP, blood pressure; TR, tricuspid regurgitation.
a
Adjusted for TDI-MPI z-score, LV shortening fraction, LVEDD z-score, degree of mitral regurgitation, and milrinone use.