| Methods |
RCT comparing candesartan versus placebo in patients with chronic heart failure and preserved left‐ventricular ejection fraction. |
| Data |
3025 patients were randomised (1514/1509, respectively in each treatment group), including two patients who mistakenly received randomisation numbers but had no other data recorded and never received study medication. |
| Comparisons |
Onsite assessment (local investigator blinded) versus assessment by an AC blinded to allocated treatment. |
| Outcomes |
The outcome selected was admission to hospital for chronic heart disease or cardiovascular death. The study's primary outcome was cardiovascular death or admission to hospital for chronic heart failure. |
| Notes |
The study was identified because it was include in a review of six RCTs (Granger 2008). Data related to the number of events in each treatment group resulting from onsite‐assessor and AC assessments were extracted from this review . |
| Risk of bias |
| Item |
Authors' judgement |
Description |
| Method for selecting cases to adjudicate? |
No |
All suspect events adjudicated were identified by onsite assessor who was blinded to allocated treatment. |
