O' Connor 2005.

Methods	RCT comparing bucindolol versus placebo in patients who had moderate to severe heart failure.
Data	2708 patients were analysed (1354/1354, respectively in each group).
Comparisons	Onsite assessment (local investigator blinded) versus assessment by an AC blinded to allocated treatment.
Outcomes	The outcome selected was non fatal myocardial infarction. The study's primary outcome was total mortality.
Notes
Risk of bias
Item	Authors' judgement	Description
Method for selecting cases to adjudicate?	No	All suspect events adjudicated were identified by onsite assessor who was blinded to allocated treatment.