Shumaker 2003.

Methods	RCT comparing oestrogen plus progestin versus placebo in post‐menopausal women.
Data	4532 patients were randomised (2229/2303, respectively in each treatment group).
Comparisons	Onsite assessment (local investigator blinded) versus assessment by an AC blinded to allocated treatment.
Outcomes	The outcome selected was incidence of dementia.This was the study's primary outcome.
Notes
Risk of bias
Item	Authors' judgement	Description
Method for selecting cases to adjudicate?	No	All suspect events adjudicated were identified by onsite assessor who was blinded to treatment allocation.