Wiviott 2007.

Methods	RCT comparing prasugrel versus clopidogrel in patients with acute coronary syndromes.
Data	13,608 patients were randomised (6813/6795, respectively in each treatment group).
Comparisons	Onsite assessment (blinded local investigator) versus assessment by an AC blinded to allocated treatment.
Outcomes	The outcome selected was myocardial infarction. The study's primary outcome was death from cardiovascular causes, non fatal myocardial infarction, or non fatal stroke.
Notes	The study was identified because it was included in a review (Serebruany 2012). Data related to the number of events in each treatment group resulting from onsite‐assessor and AC assessments were extracted from this review.
Risk of bias
Item	Authors' judgement	Description
Method for selecting cases to adjudicate?	No	All suspect events adjudicated were identified by onsite assessor who was blinded to allocated treatment.

AC: adjudication committee
 RCT: randomised controlled trial