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. 2020 Mar 5;96(2):260–279. doi: 10.1111/php.13217

Figure 4.

Figure 4

Verification of PDT efficacy using power Doppler US imaging. (A–C) Feline cutaneous squamous cell carcinoma imaged prior to Fospeg/Foscan‐PDT, 1 and 24 h post‐PDT at 652 nm. (D–E) Vascularity (FA) and blood volume (CWFA) calculated computationally from pixel analysis of power Doppler US signatures of five tumors. Scale bar = 1 cm. A reduction in FA from 29.9% to 7.8% and in CWFA from 17.1% to 3.8% occurred from therapy onset to 24 h afterward. Slight increase in vascularity at the 1‐h post‐PDT mark was thought to be attributable to partial blood vessel relaxation prior to full closure. Adapted with permission from 51.