Table 1.
Demographic and Laboratory Data of the Study Population
| Variable | AD | ACLF |
|---|---|---|
| n = 52 | n = 57 | |
| Age, years | 58 (50‐67) | 59 (49‐66) |
| Etiology | ||
| Alcohol | 32 | 33 |
| Viral | 0 | 11 |
| NASH | 10 | 6 |
| Biliary | 3 | 2 |
| Other | 7 | 5 |
| Male | 29 | 40 |
| SOFA score | 4 (3‐6) | 8 (6‐11) |
| CLIF‐SOFA score | 60 (47‐108) | 87 (74‐97) |
| CLIF‐AD score | 51 (42‐57) | |
| CLIF‐ACLF score | 53 (45‐60) | |
| MELD | 15 (11‐21) | 27 (23‐35) |
| Child‐Turcotte‐Pugh, points | 9 (7‐10) | 10 (8‐12) |
| Medication on admission | ||
| antibiotics | 25 | 32 |
| Betablocker | 22 | 36 |
| Antiviral | 0 | 6 |
| Lactulose | 21 | 19 |
| Rifaximin | 4 | 14 |
| Ascites | ||
| No | 9 | 2 |
| Minimal | 18 | 25 |
| Moderate | 22 | 18 |
| Severe | 3 | 12 |
| Reason(s) for decompensation | ||
| (Suspected) infection | 10 | 24 |
| Ascites | 23 | 17 |
| Encepalopathy | 7 | 12 |
| Multiorgan failure | 0 | 2 |
| Variceal bleeding | 6 | 4 |
| Alcoholic hepatitis | 5 | 5 |
| Other | 1 | 2 |
| Hemoglobin, g/dL | 80 (86‐110) | 85 (77‐99) |
| Na, mmol/L | 136 (132‐139) | 135 (132‐141) |
| Urea, mmol/L | 5 (3‐8) | 8 (4‐9) |
| Creatinine, µmol/L | 73 (54‐109) | 211 (134‐282) |
| Bilirubin, µmol/L | 39 (28‐101) | 100 (40‐381) |
| Gamma glutamyl transpeptidase, IU/L | 77 (43‐145) | 70 (42‐158) |
| Alkaline phosphatase, IU/L | 120 (82‐181) | 116 (80‐142) |
| Aspartate aminotransferase, IU/L | 62 (44‐100) | 65 (40‐108) |
| Albumin, g/L | 29 (26‐33) | 29 (24‐33) |
| Platelets × 109/L | 88 (62‐127) | 70 (38‐107) |
| Fibrinogen, g/L | 2.2 (1.4‐2.9) | 1.8 (1.1‐2.5) |
| INR | 1.4 (1.3‐1.8) | 1.7 (1.4‐2.6) |
| APTT, seconds | 36 (30‐43) | 41 (33‐56) |
Abbreviations: APTT, activated partial thromboplastin time; INR, international normalized ratio; NASH, nonalcoholic steatohepatitis.