Figure 3.

Individual differences in cocaine‐induced impairment in decision making are not associated with an increase in escalation of cocaine self‐administration. A, Rats in both the impaired and unaffected groups displayed a robust increase in the amount of cocaine self‐administered over the 19 daily 12‐h long‐access sessions, indicative of a loss of control over drug intake. B, Similarly, there was no difference in the escalation ratio on the last day of extended access between groups over extended access sessions, suggesting that there was no difference in the propensity to lose control over cocaine intake between the two populations. C, Escalation of cocaine self‐administration was not predicted by baseline decision‐making performance measured prior to drug exposure (the shaded area represents the 95% confidence interval). Data are presented as mean ± standard error of the mean (SEM) or individual data points