Table 1.
MPNs | |||
---|---|---|---|
No. patients | 40 | ||
Gender | |||
Male | 17 (42·5) | ||
Female | 23 (57·5) | ||
Median age, years (range) | 64 (32–86) | ||
Pathology | |||
(A) Essential thrombocythaemia | 22/40 | ||
Platelet count 109/l (mean ± SD) | 691·18 ± 264·40 | ||
Haematocrit (mean ± SD) | 41·00 ± 5·50 | ||
JAK2 allele burden (mean ± SD) | 17·67 ± 15·46 | ||
CALR mut exon 9 – Type 2 | 2/22 (9%) | ||
(B) Polycythaemia vera | 13/40 | ||
Platelet count 109/l (mean ± SD) | 415·08 ± 176·96 | ||
Haematocrit (mean ± SD) | 48·93 ± 3·06 | ||
JAK2 allele burden (mean ± SD) | 47·85 ± 34·18 | ||
CALR mut exon 9 – Type 2 | 0/13 (0%) | ||
(C) Myelofibrosis | 5/40 | ||
Platelet count 109/l (mean ± SD) | 461·60 ± 32·18 | ||
Haematocrit (mean ± SD) | 43·64 ± 7·73 | ||
JAK2 allele burden (mean ± SD) | 12·63 ± 11·74 | ||
CALR mut exon 9 – Type 2 | 1/5 (20%) |