Fig. 6.

Allele frequency estimation for somatic deletions. Results are grouped by deletion length, denoted as interval at the top of the plot. The horizontal axis shows the true allele frequency; the vertical axis shows the error between predicted allele frequency and truth. The observable true allele frequencies are a result of the subclone structure used in the simulation process outlined in Fig. 2. Note that there are only few data points for allele frequencies below 0.125 with variant sizes above 30 bp. In consequence, those box plots have to be considered with care