Table 5.
Risk of persistence of MetS (hazard ratio, 95% confidence interval) based on changes in its components from baseline to Phase II of the study, by gender
| Variables | Men | Women | Total | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Crude HR (95% CI) | Model I HR (95% CI) | Model II HR (95% CI) | Crude HR (95% CI) | Model I HR (95% CI) | Model II HR (95% CI) | Crude HR (95% CI) | Model I HR (95% CI) | Model II HR (95% CI) | |
| FBG mg/dL | |||||||||
| ≤−19.9 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| −20-5.9 | 0.76 (0.52-1.1) | 0.75 (0.51-1.1) | 1.03 (0.54-1.9) | 1.2 (0.84-1.7) | 1.2 (0.84-1.72) | 1.39 (0.61-3.1) | 0.98 (0.76-1.27) | 0.96 (0.75-1.25) | 1.24 (0.77-2) |
| 6-33.9 | 0.9 (0.63-1.28) | 0.93 (0.65-1.3) | 1 (0.56-1.78) | 1.1 (0.78-1.6) | 1.1 (0.78-1.6) | 0.87 (0.4-1.89) | 1.02 (0.79-1.31) | 1.03 (0.8-1.33) | 0.97 (0.62-1.53) |
| ≥34 | 0.9 (0.63-1.28) | 0.9 (0.64-1.29) | 0.96 (0.54-1.7) | 1.07 (0.75-1.5) | 1.07 (0.74-1.5) | 0.88 (0.42-1.87) | 0.98 (0.77-1.26) | 0.98 (0.77-1.27) | 0.96 (0.62-1.48) |
| P for trend | 0.783 | 0.994 | 0.885 | 0.814 | 0.81 | 0.571 | 0.977 | 0.964 | 0.635 |
| SBP (mmHg) | |||||||||
| ≤−10 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| −9.7-2.5 | 0.74 (0.49-1.1) | 0.74 (0.49-1.1) | 0.7 (0.36-1.38) | 1.27 (0.88-1.8) | 1.28 (0.88-1.8) | 1.18 (0.5-2.65) | 1.04 (0.79-1.36) | 1.03 (0.78-1.35) | 1 (0.62-1.6) |
| 2.6-15.5 | 0.99 (0.66-1.49) | 0.99 (0.66-1.5) | 1.42 (0.71-2.8) | 1.18 (0.8-1.7) | 1.24 (0.84-1.8) | 0.94 (0.37-2.38) | 1.1 (0.84-1.45) | 1.12 (0.85-1.48) | 1.1 (0.64-1.79) |
| ≥15.6 | 1 (0.7-1.48) | 1 (0.69-1.47) | 1.1 (0.58-2) | 1.7 (1.15-2.55) | 1.72 (1.16-2.6) | 1.56 (0.62-3.9) | 1.35 (1.03-1.76) | 1.32 (1.002-1.7) | 0.99 (0.61-1.6) |
| P for trend | 0.506 | 0.529 | 0.509 | 0.023 | 0.016 | 0.505 | 0.028 | 0.039 | 0.973 |
| DBP (mmHg) | |||||||||
| ≤−10.5 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| −10 to−2.5 | 1.05 (0.7-1.55) | 1.08 (0.73-1.6) | 0.79 (0.42-1.5) | 1.46 (0.99-2.1) | 1.46 (0.99-2.2) | 1.59 (0.77-3.2) | 1.24 (0.95-1.64) | 1.27 (0.97-1.68) | 0.95 (0.6-1.5) |
| −2 to 6.5 | 1.41 (0.97-2.1) | 1.45 (0.98-2.1) | 1.26 (0.66-2.4) | 1.64 (1.12-2.4) | 1.69 (1.15-2.5) | 1.01 (0.42-2.4) | 1.5 (1.14-1.95) | 1.56 (1.19-2.04) | 1.12 (0.67-1.87) |
| ≥ 6.6 | 1.23 (0.84-1.8) | 1.26 (0.85-1.9) | 1.14 (0.63-2) | 1.35 (0.92-2) | 1.43 (0.96-2.1) | 1.13 (0.45-2.8) | 1.27 (0.97-1.67) | 1.34 (1.02-1.78) | 1.02 (0.63-1.63) |
| P for trend | 0.141 | 0.116 | 0.421 | 0.101 | 0.51 | 0.735 | 0.034 | 0.013 | 0.816 |
| TG (mg/dL) | |||||||||
| ≤−101 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| −100 to−43 | 0.65 (0.45-0.92) | 0.62 (0.43-0.9) | 0.39 (0.21-0.7) | 1.23 (0.85-1.8) | 1.23 (0.85-1.8) | 0.93 (0.36-2.3) | 0.9 (0.7-1.16) | 0.88 (0.68-1.13) | 0.5 (0.3-0.83) |
| −42-9.25 | 0.61 (0.43-0.87) | 0.6 (0.42-0.9) | 0.46 (0.25-0.8) | 1.26 (0.87-1.8) | 1.26 (0.87-1.8) | 1.47 (0.71-3.1) | 0.89 (0.68-1.14) | 0.87 (0.67-1.13) | 0.75 (0.47-1.2) |
| ≥9.26 | 1 (0.7-1.43) | 1 (0.7-1.43) | 0.58 (0.3-1.1) | 1.25 (0.88-1.8) | 1.25 (0.88-1.8) | 0.97 (0.48-2) | 1.11 (0.87-1.43) | 1.11 (0.86-1.42) | 0.7 (0.44-1.12) |
| P for trend | 0.789 | 0.822 | 0.309 | 0.219 | 0.853 | 0.773 | 0.462 | 0.458 | 0.526 |
| HDL-C (mg/dL) | |||||||||
| ≤−19 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| −18.9 to−10 | 0.77 (0.55-1.1) | 0.77 (0.55-1.1) | 0.87 (0.49-1.6) | 0.93 (0.66-1.3) | 0.93 (0.65-1.3) | 1.01 (0.4-2.51) | 0.85 (0.66-1.09) | 0.85 (0.67-1.09) | 0.83 (0.52-1.32) |
| −9 to−2 | 1.29 (0.9-1.87) | 1.28 (0.88-1.8) | 1.25 (0.66-2.3) | 0.79 (0.56-1.1) | 0.79 (0.55-1.1) | 0.92 (0.43-2) | 0.96 (0.74-1.23) | 0.97 (0.75-1.25) | 1.14 (0.71-1.83) |
| ≥−1 | 0.75 (0.52-1.1) | 0.78 (0.54-1.1) | 1.34 (0.7-2.52) | 0.66 (0.46-09) | 0.66 (0.45-1) | 0.69 (0.32-1.5) | 0.72 (0.56-0.93) | 0.74 (0.57-0.96) | 0.94 (0.59-1.49) |
| P for trend | 0.468 | 0.645 | 0.211 | 0.016 | 0.017 | 0.297 | 0.036 | 0.06 | 0.894 |
| WC (cm) | |||||||||
| ≤1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 2-5 | 0.94 (0.67-1.31) | 0.97 (0.69-1.4) | 0.73 (0.43-1.3) | 1.17 (0.79-1.7) | 1.17 (0.79-1.7) | 0.86 (0.36-2.1) | 1.07 (0.82-1.38) | 1.07 (0.83-1.38) | 0.76 (0.49-1.16) |
| 6-10 | 1.18 (0.84-1.67) | 1.3 (0.93-1.9) | 1.45 (0.77-2.7) | 1.55 (1.1-2.19) | 1.56 (1.1-2.2) | 1.64 (0.8-3.37) | 1.36 (1.07-1.7) | 1.44 (1.13-1.8) | 1.4 (0.9-2.21) |
| ≥11 | 1 (0.68-1.46) | 1.1 (0.75-1.6) | 1.19 (0.61-2.3) | 1.51 (1.07-2.1) | 1.52 (1.1-2.15) | 1.62 (0.78-3.36) | 1.26 (0.98-1.62) | 1.32 (1.03-1.7) | 1.14 (0.72-1.82) |
| P for trend | 0.644 | 0.28 | 0.335 | 0.007 | 0.007 | 0.104 | 0.018 | 0.005 | 0.248 |
| BMI (kg/m2) | |||||||||
| ≤-0.93 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| -0.9 to 0.7 | 0.78 (0.55-1.1) | 0.79 (0.55-1.1) | 0.8 (0.44-1.5) | 0.88 (0.6-1.3) | 0.89 (0.6-1.3) | 0.76 (0.31-1.81) | 0.83 (0.64-1.07) | 0.83 (0.65-1.09) | 0.87 (0.54-1.4) |
| 0.8-2.6 | 0.92 (0.64-1.3) | 0.94 (0.66-1.3) | 1 (0.55-1.83) | 0.75 (0.51-1.1) | 0.75 (0.51-1.1) | 0.89 (0.37-2.15) | 0.84 (0.65-1.08) | 0.85 (0.66-1.1) | 0.8 (0.5-1.31) |
| ≥2.7 | 0.73 (0.49-1.09) | 0.79 (0.52-1.2) | 0.67 (0.3-1.41) | 0.87 (0.62-1.2) | 0.88 (0.62-1.2) | 0.93 (0.38-2.28) | 0.81 (0.63-1.05) | 0.84 (0.65-1.1) | 0.69 (0.4-1.18) |
| P for trend | 0.242 | 0.433 | 0.504 | 0.391 | 0.409 | 0.957 | 0.143 | 0.233 | 0.166 |