TABLE 2.

Effects of pyomelanin secretion on the readout system^a

Antifungal agent		Agreement (%) at 570 nm for:		Agreement (%) at 620 nm for:
	Visual vs Vizion	Visual vs spectrophotometric	Vizion vs spectrophotometric	Visual vs spectrophotometric	Vizion vs spectrophotometric
	MICs within 1 dilution	MICs within 1 dilution	MICs within 1 dilution	MICs identical	MICs within 1 dilution
Itraconazole	100	81.5	80	92.3	80
Voriconacozole	100	81.5	70	92.3	70
Posaconazole	100	81.5	80	92.3	80
Fluconazole	70	56.25	50	92.3	60
Amphotericin B	100	87.5	80	100	80
5-Flucytosine	100	93.75	90	100	90
Caspofungin	100	93.75	90	100	90
Micafungin	100	93.75	90	100	90
Anidalufungin	100	100	100	100	100

^aPercentage agreement between visual, SWIN, and spectrophotometric readouts at 570 nm and 620 nm for the Sensititre YeastOne assay for isolates of 16 M. mycetomatis strains. The agreement is presented as MIC₉₀ within a one-step dilution difference.