TABLE 1.
Antibiotic | MIC (μg ml−1) |
|||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
JE2 |
SA564 |
8325-4 |
||||||||||
WT | sle1 | mecA | clpXI265E | clpXI265E, sle1 | clpXI265E, mecA | WT | sle1 | clpXI265E | WT | sle1 | clpXI265E | |
Oxacillin | 32–64 | 0.5 | 0.75 | >256 | 0.5 | 1 | 0.5 | 0.5 | 0.75 | 0.38 | 0.25 | 0.5 |
Imipenem | 0.12 | 0.12 | 0.12 | 0.25 | 0.25 | 0.25 | 0.5 | 0.12 | 0.12 | 0.12 | 0.12 | 0.12 |
Cefotaxime | 8 | 2–4 | 2 | 64 | 2 | 4 | 4 | 2 | 4 | 1 | 1 | 1 |
Cefoxitin | 16 | 4 | 4 | 32 | 4 | 4 | 4 | 4 | 4 | 2 | 2 | 4 |
Cefepime | 4 | 2 | 2 | >32 | 4-8 | 4 | 4 | 4 | 4 | 2 | 1 | 2 |
Ertapenem | 0.5 | 0.12 | 0.25 | >2 | 0.12 | 0.25 | 0.5 | 0.12 | 0.25 | 0.12 | 0.12 | 0.25 |
Meropenem | 0.25 | 0.12 | 0.12 | 2 | 0.12 | 0.12 | 0.12 | 0.06 | 0.25 | 0.12 | 0.06 | 0.12 |