Table 4.

Associations Between Average Blood Glucose Levels Within 24 Hours After ICU Admission and Clinical Outcomes

Average Blood Glucose Levels (mg/dL)	Crude		Adjusted*		Adjusted*
					Without Diabetes		Diabetes
	OR/HR	95% CI	OR/HR	95% CI	OR/HR	95% CI	OR/HR	95% CI
Hospital mortality
<60	1.09	0.15–8.17	0.70	0.09–5.48	1.35	0.16–11.72	–	–
60–80	2.14	1.40–3.26	1.28	0.81–2.03	1.34	0.78–2.30	1.07	0.44–2.63
80–110	1.15	0.94–1.41	1.11	0.90–1.38	1.11	0.87–1.40	1.11	0.65–1.89
110–140	1	Reference	1	Reference	1	Reference	1	Reference
140–180	1.33	1.10–1.61	1.15	0.94–1.41	1.27	1.01–1.59	0.98	0.64–1.51
180–200	1.71	1.27–2.28	1.46	1.07–1.98	1.66	1.11–2.48	1.38	0.82–2.32
≥200	1.59	1.25–2.02	1.23	0.96–1.58	1.77	1.25–2.52	1.09	0.71–1.68
ICU mortality
<60	–	–	–	–	–	–	–	–
60–80	3.26	1.12–9.50	2.95	0.97–8.98	2.65	0.74–9.45	6.05	0.53–69.29
80–110	0.97	0.49–1.91	1.19	0.59–2.40	1.31	0.64–2.69	–	–
110–140	1	Reference	1	Reference	1	Reference	1	Reference
140–180	1.93	1.12–3.32	1.51	0.86–2.64	1.52	0.82–2.81	2.29	0.56–9.40
180–200	3.40	1.68–6.86	2.57	1.23–5.34	3.52	1.57–7.88	1.40	0.21–9.38
≥200	4.74	2.74–8.18	3.31	1.86–5.88	5.08	2.61–9.89	3.06	0.76–12.28
28-day mortality
<60	–	–	–	–	–	–	–	–
60–80	1.99	1.40–2.82	1.23	0.87–1.75	1.18	0.77–1.80	1.34	0.70–2.55
80–110	1.14	0.96–1.35	1.11	0.93–1.31	1.09	0.90–1.31	1.15	0.76–1.7
110–140	1	Reference	1	Reference	1	Reference	1	Reference
140–180	1.21	1.04–1.42	1.08	0.92–1.27	1.14	0.95–1.38	1.00	0.71–1.39
180–200	1.51	1.18–1.93	1.36	1.06–1.74	1.47	1.06–2.03	1.38	0.91–2.08
≥200	1.37	1.12–1.68	1.15	0.94–1.41	1.66	1.25–2.20	1.01	0.72–1.44

Notes: *Adjusted for age, sex, ethnicity, type of admission, SAPS II on admission, mechanical ventilation on first day, renal replacement therapy on first day, and Elixhauser Comorbidity Index (SID30).

Abbreviations: ICU, intensive care unit; OR, odds ratio; HR, hazard ratio; CI, confidence interval.