Table 6.
Associations Between Maximum Blood Glucose Levels Within 24 Hours After ICU Admission and Clinical Outcomes
Maximum Blood Glucose Levels (mg/dL) | Crude | Adjusted* | Adjusted* | |||||
---|---|---|---|---|---|---|---|---|
Without Diabetes | Diabetes | |||||||
OR/HR | 95% CI | OR/HR | 95% CI | OR/HR | 95% CI | OR/HR | 95% CI | |
Hospital mortality | ||||||||
<60 | 3.12 | 0.38–25.52 | 2.29 | 0.26–20.53 | 6.22 | 0.54–72.28 | – | – |
60–80 | 3.09 | 1.73–5.52 | 1.86 | 0.98–3.52 | 2.58 | 1.26–5.29 | 0.68 | 0.14–3.30 |
80–110 | 1.17 | 0.91–1.51 | 1.09 | 0.83–1.42 | 1.05 | 0.79–1.41 | 1.24 | 0.63–2.43 |
110–140 | 1 | Reference | 1 | Reference | 1 | Reference | 1 | Reference |
140–180 | 1.36 | 1.11–1.66 | 1.26 | 1.02–1.55 | 1.32 | 1.05–1.66 | 1.13 | 0.68–1.87 |
180–200 | 1.37 | 1.02–1.84 | 1.08 | 0.80–1.47 | 1.12 | 0.78–1.60 | 1.10 | 0.59–2.05 |
≥200 | 1.63 | 1.32–2.00 | 1.18 | 0.95–1.46 | 1.40 | 1.07–1.84 | 1.14 | 0.72–1.79 |
ICU mortality | ||||||||
<60 | – | – | – | – | – | – | – | – |
60–80 | 3.63 | 0.84–15.71 | 2.81 | 0.61–12.90 | 3.46 | 0.73–16.38 | – | – |
80-110 | 0.64 | 0.26–1.60 | 0.69 | 0.27–1.75 | 0.59 | 0.22–1.61 | 2.85 | 0.16–50.54 |
110–140 | 1 | Reference | 1 | Reference | 1 | Reference | 1 | Reference |
140–180 | 1.31 | 0.73–2.35 | 1.00 | 0.55–1.83 | 0.98 | 0.53–1.84 | 2.23 | 0.22–22.38 |
180–200 | 1.29 | 0.54–3.05 | 0.82 | 0.34–1.99 | 1.09 | 0.45–2.68 | – | – |
≥200 | 3.41 | 2.03–5.73 | 1.99 | 1.16–3.42 | 2.14 | 1.17–3.91 | 5.87 | 0.74–46.39 |
28-day mortality | ||||||||
<60 | – | – | – | – | – | – | – | – |
60–80 | 2.14 | 1.27–3.60 | 1.20 | 0.71–2.03 | 1.31 | 0.71–2.41 | 1.02 | 0.36–2.86 |
80–110 | 1.18 | 0.96–1.44 | 1.10 | 0.90–1.35 | 1.08 | 0.86–1.35 | 1.20 | 0.72–2.02 |
110–140 | 1 | Reference | 1 | Reference | 1 | Reference | 1 | Reference |
140–180 | 1.18 | 1.00–1.39 | 1.10 | 0.93–1.30 | 1.15 | 0.96–1.38 | 1.01 | 0.68–1.50 |
180–200 | 1.18 | 0.92–1.51 | 0.97 | 0.76–1.24 | 0.91 | 0.67–1.23 | 1.17 | 0.73–1.88 |
≥200 | 1.40 | 1.18–1.66 | 1.09 | 0.92–1.29 | 1.28 | 1.03–1.59 | 1.05 | 0.73–1.49 |
Notes: *Adjusted for age, sex, ethnicity, type of admission, SAPS II on admission, mechanical ventilation on first day, renal replacement therapy on first day, and Elixhauser Comorbidity Index (SID30).
Abbreviations: ICU, intensive care unit; OR, odds ratio; HR, hazard ratio; CI, confidence interval.