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. 2009 May 20;49(9):1931–1943. doi: 10.1111/j.1537-2995.2009.02222.x

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© 2009 American Association of Blood Banks

This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response. It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency.

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Data on virus inactivation by S/D treatment of all 308 studies, including robustness studies with significantly reduced concentrations of solvent and detergent. Mean LRF values are plotted versus the first time point at which virus inactivation to below the limit of detection or the highest reduction factor was achieved. Shown are the mean values of inactivation and the ranges of inactivation for the corresponding time points: 0 to 5 minutes (n = 58), 5 to 16 minutes (n = 26), 30 minutes (n = 27), 60 minutes (n = 42), 120 minutes (n = 73), 180 minutes (n = 17), 240 minutes (n = 16), 300 minutes (n = 1), 360 minutes (n = 21), and 480 minutes (n = 26). For viruses tested, please see text. Vertical bars show the range of inactivation.