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. 2020 Apr 21;8:260. doi: 10.3389/fcell.2020.00260

FIGURE 4.

FIGURE 4

The potential applications of mesenchymal stem cells (MSCs) that originate from endothelial cells (ECs) in tissue engineering. ECs from patients isolated from tissues, such as skin or blood, can be stimulated to undergo endothelial to mesenchymal transition (EndMT) to generate MSCs. These multipotent MSCs can be differentiated into various cell types, which may be used to form desired tissue types that can be transplanted into patients.