Table 2.
Perinatal outcomes among pregnant patients with SARS-CoV-2 infection and death
| Outcome | Case 1 | Case 2 | Case 3 | Case 4 | Case 5 | Case 6 | Case 7 |
|---|---|---|---|---|---|---|---|
| Fetal death | Yes | No | No | Yesa | No | Yesa | No |
| Gestational age (wk) | 30 3/7 | 38 3/7 | 30 5/7 | 24 0/7 (undelivered) | 36 0/7 | 24 0/7 (undelivered) | 28 0/7 |
| Neonatal demise | n/a | No | No | n/a | No | n/a | Yes (twins) |
| Mode of delivery | NSVD | Cesarean | Cesarean | n/a | Cesarean | n/a | Cesarean |
| Birthweight (g) | 1700 | 2800 | 2100 | n/a | 3200 | n/a | 1180; 1340 |
| Apgar score (1.5 min) | 0, 0 | 8, 9 | 9, 10 | n/a | 7, 9 | n/a | 8, 9; 7, 9 |
| DCDA twin gestation | No | No | No | Yes | No | Yes | Yes |
| SARS-CoV-2 NAT | n/a | Negative | Negativeb | n/a | Negative | n/a | Negative |
| Neonatal pneumonia | n/a | No | Yes | n/a | No | n/a | No; no |
| Neonatal lymphopenia | n/a | No | Yes | n/a | No | n/a | No; no |
In no instance was magnesium sulfate given intrapartum nor antenatal for the purpose of neuroprotection, and no patient in the series had preeclampsia.
DCDA, dichorionic diamniotic; n/a, not applicable; NSVD, normal spontaneous vaginal delivery; RT-PCR NAT, reverse transcription polymerase chain reaction nucleic acid testing; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.
Hantoushzadeh et al. Maternal death due to coronavirus disease 2019. Am J Obstet Gynecol 2020.
24-week singleton (case 4) or DCDA twin gestation (case 6) in utero at the time of maternal death, undelivered
As detailed in the case description, case 3 was negative on day of life 1 but converted to positive on day of life 7.