Table 5.

Inflammatory gene expression in whole blood for horses following surgical correction of ≥ 360 degree large colon volvulus that lived and horses that died before and after treatment with 150 mg/kg ethyl pyruvate or lactated Ringer's solution control.

Gene	Treatment	Survive	Time	N =	Mean	Std Dev
IL-10	Control	Lived	PO	5	6.6	1.2
			24 PO	5	9.4	1.3
		Died	PO	5	6.4	2.1
			24 PO	5	8	1.8
	Ethyl pyruvate	Lived	PO	7	6.7	2.1
			24 PO	7	8.6	1
		Died	PO	5	7.1	0.9
			24 PO	5	7.5	0.2
HMGB-1	Control	Lived	PO	5	3	0.6
			24 PO	5	2.8	0.5
		Died	PO	5	3.1	0.1
			24 PO	5	2.3	0.4
	Ethyl pyruvate	Lived	PO	7	2.3	1
			24 PO	7	2.4	0.8
		Died	PO	5	3.2	2.3
			24 PO	5	3.5	1.3
IL-6	Control	Lived	PO	5	10.2	2
			24 PO	5	13.2	2
		Died	PO	5	13.1	2.2
			24 PO	5	12.1	1.3
	Ethyl pyruvate	Lived	PO	7	11.8	1.3
			24 PO	7	12.3	1.4
		Died	PO	5	10	6.2
			24 PO	5	12.6	0.7
TNFa	Control	Lived	PO	5	5	0.7
			24 PO	5	3.9	1.1
		Died	PO	5	5.4	1.9
			24 PO	5	4.7	1.1
	Ethyl pyruvate	Lived	PO	7	5.3	0.5
			24 PO	7	5.1	0.6
		Died	PO	5	6	0.1
			24 PO	5	6	0.1

Inflammatory gene expression as ΔCT in whole blood from horses after surgical correction of large colon volvulus. Blood samples were collected post-operatively (PO) when horses returned to their stalls following anesthetic recovery and 24 h later (24 PO) after treated horses received 150 mg/kg ethyl pyruvate in 1 liter lactate Ringer's solution (LRS), intravenously (IV) as a controlled rate infusion (CRI) every 6 h for 4 treatments or control horses received 1 liter LRS, IV as a CRI, every 6 h for 4 treatments.