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. 2020 Apr 21;11:458. doi: 10.3389/fphar.2020.00458

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Copyright © 2020 Zhang, Guo, Wang, Wang, Wang, Wu, Li, Wang and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Danqi Pill (DQP) activated HIF1α/PGC1α signaling pathway in heart failure (HF) post-acute myocardial infarction (AMI) rats. (A) Western blot analysis the expressions of PPARα, RXRα, and PGC-1α in the four groups. Densitometric analysis was showed. (B) Effects of DQP on expressions of HIF-1α and PHD2 in HF post-AMI Rats; WB bands and protein quantitative results of HIF-1α and PHD2 in heart tissues of rats. ^# p < 0.05, ^## p < 0.01, ^###P < 0.001 compared with sham; ^*P < 0.05, ^**P < 0.01, ^***P < 0.001 compared with model. N =3 per group.