Skip to main content
. Author manuscript; available in PMC: 2021 Jan 1.
Published in final edited form as: Prog Retin Eye Res. 2019 Aug 11;74:100773. doi: 10.1016/j.preteyeres.2019.100773

Figure 18:

Figure 18:

Quick-freeze deep-etch (QFDE) electron microscopy image of mouse posterior sclera, revealing layers of differentially oriented collagen lamellae in 3D. On the right side of the image (*) can be seen an area of partially etched, vitrified ice - a product of the “freeze-fracture” processing that can preserve native hydrated structure more closely than is possible with conventional electron microscopy sample preparation. Scale bar: 2 μm. Figure reproduced from (Ismail et al., 2017) with permission of Elsevier Ltd.