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. 2020 Apr 24;15:2921–2933. doi: 10.2147/IJN.S247443

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© 2020 Wang et al.

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Formulation and characterization of prodrug-based nanoparticles. (A) Schematic illustration of the procedure for self-assembly of 2DA-FITC-PTX NPs. (B) TEM images of 2DA-FITC-PTX NPs. (C) DLS of 2DA-FITC-PTX NPs. (D) In vitro release of PTX in different buffer. PTX concentration was measured by HPLC. The release was expressed as mean ± standard deviation based on triplicate experiments.

Abbreviations: 2DA-FITC-PTX NPs, 2-glucosamine-fluorescein-5(6)-isothiocyanate-glutamic acid-paclitaxel nanoparticles; TEM, transmission electron microscopy; DLS, dynamic light scattering; PTX, paclitaxel; HPLC, high-performance liquid chromatography.