Table 2.
Comparison of MMR Tested by IHC Technique and MSI Status Analyzed by PCR-CE Method in CRC Patients
| IHC | PCR-CE | Total | Kappa Value | p-value | |
|---|---|---|---|---|---|
| MSI-H | MSI-L/MSS | ||||
| dMMR | 62 | 69 | 131 | 0.547 | <0.001 * |
| pMMR | 12 | 595 | 607 | ||
| Total | 74 | 664 | 738 | ||
Notes: *p-value was calculated by Pearson chi-square test, and statistical significance.
Abbreviations: IHC, immunohistochemical; PCR-CE, PCR-capillary electrophoresis; CRC, colorectal cancer; MSI, microsatellite instability; MSS/MSI-L, microsatellite stable or low microsatellite instability; MSI-H, high microsatellite instability; MMR, mismatch repair; dMMR, deficient MMR; pMMR, proficient MMR.