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. 2020 Mar 29;12(3):e7453. doi: 10.7759/cureus.7453

Table 2. Transthoracic echocardiography parameters and associated valve pathology stratified by the presence of left atrial thrombus in the study population.

LA: left atrial; MR: mitral regurgitation; AR: atrial regurgitation; AS: atrial stenosis; TR: tricuspid regurgitation; ASD: atrial septal defect; SD: standard deviation; LV: left ventricular; EF: ejection fraction; RV: right ventricular

Pathologies and defects Values LA thrombus P-value
Present Absent
Total patients 256 64 192 -
Associated valve pathologies, n (%) 137 (53.5) 53 (82.8) 84 (43.8) <0.001
MR, n (%) 44 (17.2) 16 (25) 28 (14.6) 0.056
Mild, n (%) 28 (63.6) 10 (62.5) 18 (64.3) 0.906
Moderate, n (%) 16 (36.4) 6 (37.5) 10 (35.7)
Severe, n (%) 0 (0) 0 (0) 0 (0)
AR, n (%) 13 (5.1) 3 (4.7) 10 (5.2) 0.869
Mild, n (%) 12 (92.3) 3 (100) 9 (90) 0.569
Moderate, n (%) 1 (7.7) 0 (0) 1 (10)
Severe, n (%) 0 (0) 0 (0) 0 (0)
AS, n (%) 12 (4.7) 5 (7.8) 7 (3.6) 0.172
Mild, n (%) 6 (50) 5 (100) 1 (14.3) 0.014
Moderate, n (%) 3 (25) 0 (0) 3 (42.9)
Severe, n (%) 3 (25) 0 (0) 3 (42.9)
TR, n (%) 125 (48.8) 49 (76.6) 76 (39.6) <0.001
Mild, n (%) 37 (29.6) 12 (24.5) 25 (32.9) 0.603
Moderate, n (%) 62 (49.6) 26 (53.1) 36 (47.4)
Severe, n (%) 26 (20.8) 11 (22.4) 15 (19.7)
ASD, n (%) 5 (2) 0 (0) 5 (2.6) 0.192
Pulmonary artery pressure, mean ±SD, mmHg 58.72 ±16.2 62.39 ±17.7 57.47 ±15.6 0.083
LV dysfunction, n (%) 44 (17.3) 19 (29.7) 25 (13.1) 0.192
Decreased EF, mean ±SD, % 54.19 ±7.2 52 ±8.5 54.94 ±6.6 0.011
RV dysfunction, n (%) 39 (15.2) 25 (39.1) 14 (7.3) <0.001
Mild, n (%) 23 (59) 13 (52) 10 (71.4) 0.237
Moderate, n (%) 16 (41) 12 (48) 4 (28.6)
Severe, n (%) 0 (0) 0 (0) 0 (0)
Vegetation, n (%) 30 (11.8) 7 (10.9) 23 (12.1) 0.802
Anterior mitral leaflet, n (%) 22 (73.3) 7 (100) 15 (65.2) 0.19
Posterior mitral leaflet, n (%) 6 (20) 0 (0) 6 (26.1)
Others, n (%) 2 (6.7) 0 (0) 2 (8.7)