SLIM SUPER IMS separation of a mixture of six iodo-TMT isotopomers in nitrogen drift gas after 1354.5 m. The [M + H]+ parent ion (458 m/z) was fragmented post-SLIM IMS separation to yield nonisobaric reporter ions (126, 127, 128, 129, 130, and 131 m/z) used to construct the arrival time distribution (bottom left), revealing the separation of the six isotopomers. IMS-MS illustration of the fragment ions is also shown (bottom left). CoM vectors (bottom right) relative to the iodo-126 (red dot). 3D structures of the iodo-TMT are displayed (top). Hydrogen atoms were removed for ease of visualization.