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. 2020 Apr 9;11:654. doi: 10.3389/fmicb.2020.00654

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Copyright © 2020 Bai, Zhang, Jin, Zhu, Zhao, Shi, Li, Guo, Guo, McManus, Wang and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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miRNAs with different expression patterns between SSD and NSD. (A) The differentially expressed miRNAs with different expression patterns. (B) The miRNAs were differential expressed throughout the three time-points. The blue line indicates the expression levels of candidate miRNAs during in vitro culture in the presence of the bile salt as strobilization stimulus (SSD). The red line indicates the expression levels of candidate miRNAs during the in vitro culture without the bile salt strobilization stimulus (NSD). The Y-axis indicates the relative expression levels of each miRNA.