Fig. 1.

Forest plot of SNPs.

Note: This table lists effect sizes and 95% confidence intervals for all 79 SNPs, ordered according to positive effect size on the outcome. The two diamonds at the bottom of the plot represent the IVW estimate from using all SNPs (“All – IVW”) together with a 95% confidence interval, and also for contrast the MR-Egger estimate (“All – Egger”) with a 95% confidence interval when using all 79 SNPs. Point estimates are positive in each case, but MR-Egger is associated with much greater uncertainty that the IVW estimate.