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. 2020 Apr 28;15(4):e0232354. doi: 10.1371/journal.pone.0232354

Table 2. Mean percentages of time spent in, under and above therapeutic range and corresponding mean differences.

Patients with CTEPH (%) Patients without CTEPH (%) Mean difference (95%CI) #
First available VTE: 3-month analysis * n = 44 n = 147
Time under therapeutic range 13 13 0 (-6 to 7)
Time in therapeutic range 69 73 -4 (-12 to 4)
Time above therapeutic range 18 14 4 (-3 to 11)
First available VTE: 6-month analysis * n = 44 n = 150
Time under therapeutic range 12 10 2 (-3 to 7)
Time in therapeutic range 72 78 -6 (-12 to -0.1)
Time above therapeutic range 16 12 4 (-1 to 9)
First PE only: 3-month analysis ** n = 35 n = 147
Time under therapeutic range 11 13 -2 (-9 to 5)
Time in therapeutic range 71 73 -2 (-10 to 7)
Time above therapeutic range 17 14 3 (-4 to 11)
First PE only: 6-month analysis ** n = 35 n = 150
Time under therapeutic range 11 10 1 (-4 to 6)
Time in therapeutic range 74 78 -4 (-10 to 3)
Time above therapeutic range 15 12 3 (-3 to 8)

* Including all patients with INR data from the first available VTE.

** Including all patients with INR data available of the first episode of PE only.

# Independent samples T-test.

Abbreviations: 95%CI, 95% confidence interval; VTE, venous thromboembolism; PE, pulmonary embolism; INR, International Normalized Ratio.