Skip to main content
. 2020 Apr 28;15(4):e0232283. doi: 10.1371/journal.pone.0232283

Fig 4. Effects of CANA on metabolites evaluated by metabolomics.

Fig 4

A) The number of significantly altered metabolites between the CANA and CON groups was plotted according to each category of metabolism. B) Volcano plot of differential metabolomics between the CON and CANA groups. Red circle indicates differential metabolites, which determined the condition of >1.5-fold increase with P<0.05 or <0.7-fold decrease with P<0.05. The green circle indicates differential metabolites associated with fatty acid metabolism. The gray circle indicates non-differential metabolites, which determined the condition of ≤1.5-fold increase and ≥0.7-fold decrease with P<0.05 and non-differential metabolites with P≥0.05. Abbreviations: CON, control; CANA, canagliflozin.