Table 2.
Cognitive domain | Baseline (prior to their receipt of chemotherapy) | 6-month after the initiation of chemotherapy | 1-year after the initiation of chemotherapy | F (P-value) |
---|---|---|---|---|
Memory | 97.4 (13.9) [67, 127] |
98.2 (19.6) [41, 140] |
98.5 (17.6) [51, 126] |
0.102 (.903) |
Psychomotor speed | 114.0 (23.5) [62, 172] |
117.4 (27.1) [39, 186] |
120.8 (26.4) [39, 190] |
7.180 (.001) |
Reaction time | 99.3 (17.1) [39, 126] |
103.0 (15.6) [36, 130] |
105.9 (12.9) [54, 133] |
18.193 (<.001) |
Complex attention | 99.8 (13.8) [64, 121] |
101.9 (19.1) [38, 121] |
106.0 (12.5) [39, 121] |
6.775 (.002) |
Cognitive flexibility | 98.4 (16.4) [58, 127] |
104.2 (20.3) [27, 126] |
108.2 (14.8) [40, 131] |
21.673 (< .001) |
Values are standardized scores and presented as mean and standard deviation (SD). The minimum and maximum values (range) were presented under the mean scores. As higher scores on reaction time and complex attention domains indicate lower cognitive function, they were reversed scored for the analysis.
P < .05 denotes significant differences between three time points.