Table 3.
The Relationship Between CLDN8/AR Co-Expression with Clinicopathological Features in Breast Cancer Patients
Factors | Total | CLDN8+/AR+ | Other Expression | P | ||
---|---|---|---|---|---|---|
N | % | N | % | |||
All | 142 | 52 | 36.7 | 90 | 63.3 | |
Age (years) | 0.570 | |||||
≤50 | 59 | 20 | 33.9 | 39 | 66.1 | |
>50 | 83 | 32 | 38.6 | 51 | 61.4 | |
T Stage | 0.561 | |||||
T1–T2 | 94 | 36 | 38.3 | 58 | 61.7 | |
T3 | 48 | 16 | 33.3 | 32 | 66.7 | |
N Stage | 0.007* | |||||
N0 | 86 | 39 | 45.3 | 47 | 54.7 | |
N1–3 | 56 | 13 | 23.2 | 43 | 76.8 | |
Histologic Grade | 0.017* | |||||
G1–G2 | 110 | 46 | 41.8 | 64 | 58.2 | |
G3 | 32 | 6 | 18.8 | 26 | 81.2 | |
Estrogen Receptor | 0.019* | |||||
Negative | 35 | 7 | 20.0 | 28 | 80.0 | |
Positive | 107 | 45 | 42.1 | 62 | 57.9 | |
Progesterone Receptor | 0.015* | |||||
Negative | 48 | 11 | 22.9 | 37 | 77.1 | |
Positive | 94 | 41 | 43.6 | 53 | 56.4 | |
HER2 | 0.508 | |||||
Negative | 99 | 38 | 38.4 | 61 | 61.6 | |
Positive | 43 | 14 | 32.6 | 29 | 67.4 | |
Ki-67 Index (%) | 0.038* | |||||
≤20 | 50 | 24 | 48.0 | 26 | 52.0 | |
>20 | 92 | 28 | 30.4 | 64 | 69.6 |
Note: *Difference was statistically significant.
Abbreviations: CLDN8, claudin-8; AR, androgen receptor.