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. 2020 Feb 7;47(6):1486–1495. doi: 10.1007/s00259-020-04695-0

Table 3.

Results of univariate survival analyses

Factor Threshold/criterion PFS OS
P value Survival time P value Survival time
Age < 70 vs. > 70 years 0.552 12 vs. 9 months 0.108 22 vs. 17 months
Resection CR vs. B/PR 0.038 13 vs. 10 months 0.121 23 vs. 15 months
IDH mutation mutant vs. wildtype < 0.001 33 vs. 9 months < 0.001 54 vs. 13 months
MGMT promoter methylated vs. non-methylated < 0.001 18 vs. 7 months < 0.001 29 vs. 12 months
KPS 100% vs. < 100% 0.143 14 vs. 9 months 0.015 29 vs. 13 months
TBRmax < 2.55 vs. > 2.55 0.072 12 vs. 7 months 0.004 24 vs. 12 months
TBRmean < 2.05 vs. > 2.05 0.112 14 vs. 7 months 0.038 25 vs. 12 months
TTP < 25 vs. > 25 min 0.005 13 vs. 7 months < 0.001 29 vs. 12 months
Slope > − 0.103 vs. < − 0.103 SUV/h 0.065 9 vs. 6 months 0.021 17 vs. 9 months
MTV 11.15 mL 0.406 12 vs. 7 months 0.048 24 vs. 12 months

B biopsy, CR complete resection, IDH isocitrate dehydrogenase, KPS Karnofsky Performance Score, MGMT, O6-methylguanine-DNA-methyltransferase, MTV, metabolic tumour volume, OS overall survival, PFS progression-free survival, PR partial resection, TBRmax maximum tumour-to-brain ratio of FET uptake, TBRmean mean tumour-to-brain ratio of FET uptake, SUV standardized uptake value