Table 3.
Results of univariate survival analyses
| Factor | Threshold/criterion | PFS | OS | ||
|---|---|---|---|---|---|
| P value | Survival time | P value | Survival time | ||
| Age | < 70 vs. > 70 years | 0.552 | 12 vs. 9 months | 0.108 | 22 vs. 17 months |
| Resection | CR vs. B/PR | 0.038 | 13 vs. 10 months | 0.121 | 23 vs. 15 months |
| IDH mutation | mutant vs. wildtype | < 0.001 | 33 vs. 9 months | < 0.001 | 54 vs. 13 months |
| MGMT promoter | methylated vs. non-methylated | < 0.001 | 18 vs. 7 months | < 0.001 | 29 vs. 12 months |
| KPS | 100% vs. < 100% | 0.143 | 14 vs. 9 months | 0.015 | 29 vs. 13 months |
| TBRmax | < 2.55 vs. > 2.55 | 0.072 | 12 vs. 7 months | 0.004 | 24 vs. 12 months |
| TBRmean | < 2.05 vs. > 2.05 | 0.112 | 14 vs. 7 months | 0.038 | 25 vs. 12 months |
| TTP | < 25 vs. > 25 min | 0.005 | 13 vs. 7 months | < 0.001 | 29 vs. 12 months |
| Slope | > − 0.103 vs. < − 0.103 SUV/h | 0.065 | 9 vs. 6 months | 0.021 | 17 vs. 9 months |
| MTV | 11.15 mL | 0.406 | 12 vs. 7 months | 0.048 | 24 vs. 12 months |
B biopsy, CR complete resection, IDH isocitrate dehydrogenase, KPS Karnofsky Performance Score, MGMT, O6-methylguanine-DNA-methyltransferase, MTV, metabolic tumour volume, OS overall survival, PFS progression-free survival, PR partial resection, TBRmax maximum tumour-to-brain ratio of FET uptake, TBRmean mean tumour-to-brain ratio of FET uptake, SUV standardized uptake value