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Analysis of KIT-specific gene expression in GIST_260. (A) Mutant allele expression in GIST_260 mRNA. Despite the low-allele-fraction in DNA, the mutant allele is highly expressed. (B) Hierarchical clustering of the top genes differentially expressed between the seven KIT-mutant cases and the six quadruple-WT (p < 10−3). GIST_260 clusters with KIT-mutant samples.
