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. 2020 Apr 28;10:7120. doi: 10.1038/s41598-020-63785-z

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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(A) Electrolyte resistance versus conductivity comparison between acrylic thread (diameter 670 µm) and surgicryl PGA (USP 0). Electrolytes were 5 mM Tris/HEPES (0.0159 S/m), 50 mM Tris/HEPES (0.141 S/m), 2.5% PBS (0.293 S/m), and 5% PBS (0.585 S/m) (B) Representative pictures depicting the parts and delivery process of fluorescein (FL, a model compound) taken after 4 minutes of applied current for 4 sutures: (i) Nylon (Ethilon, monofilament); (ii) Polyamide (Supramid, twisted and coated); (iii) Polyglactin 910 (Vycril, braided and coated); (iv) Polyglicolic acid (Surgicryl, braided and coated). Stiffness of the hydrogel was 4.3 kPa. Sample was loaded upon thread inlet segment with a 2 μL drop of a 1.0 μg/mL solution of FL. Scale bar is 2.5 mm.