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IC50 values relative to each single or combined treatment.
| AGS IC50 |
N87 IC50 |
HGC-27 IC50 |
KATO III IC50 |
|
|---|---|---|---|---|
| PTX (single drug treatment) | 5.8 | 6.4 | 3.1 | 5.4 |
| Ram (single drug treatment) | 1030 | 200 | 235 | 86 |
| PTX (in combination with Ram 100 µg/ml) | 5 | 5.7 | 2.9 | 3.9 |
Each value derived from the linear curve equation of the dose-response curve: y = mx + c (50= slope*IC50 + intercept). PTX concentration was expressed as nM and Ram as µg/ml.
