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. 2020 Apr 22;8:268. doi: 10.3389/fcell.2020.00268

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Copyright © 2020 Anzai, Yamagata and Uosaki.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Expression kinetics of the potential maturation marker genes. (A,B) Time course gene expression profiles. Mouse (left side) and human (right side) data is shown side-by-side. A red (for mouse) or blue (for human) line indicates local regression curve using locally estimated scatterplot smoothing (LOESS). (A) Candidate marker genes identified in this study. Red vertical lines indicate P0-3 in mouse and 18–19 wpc in human, which are considered as the same developmental stage. (B) Marker genes used in other literatures.