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. 2020 Apr 22;11:687. doi: 10.3389/fimmu.2020.00687

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Copyright © 2020 Ma, Zhen, Hu and Yi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Protective factors decreased in the colorectum of arg^myeKO mouse during colitis. WT and Arg^myeKO mice treated with 3.5% DSS for 9 days. Mice were sacrificed and mRNA in the colorectum of mice was isolated for further studies. qPCR analysis of ACT1 (A), IL-22 (B), IL-23 (C), OCLN (D), and COX-2 (E) in the colorectum of WT and arg^myeKO mice. **P < 0.01; ***P < 0.001. Data are representative of three independent experiments with similar results. Quantification of signal was shown in bar graphs and error bars represent mean ± SD.