FIGURE 6.

Quercetin treatment alleviated colitis depended on MDSC expansion. WT mice treated with 3.5% DSS for 8 days and monitored every day, then DAI, body weight and colon length (A) was recorded (WT, n = 3; Arg^myeKO, n = 3). Flow cytometry of MDSC in PBMC (B), spleen (C), and LPMC (F) of WT and arg^myeKO mice. Subpopulation of MDSC in PBMC (D) and spleen (E) of WT and arg^myeKO mice. *P < 0.05; **P < 0.01. Data are representative of three independent experiments with similar results. Quantification of signal was shown in bar graphs and error bars represent mean ± SD.