Table 1. Comparison of the clinical features of patients in various groups.
| Variable | Type 1 diabetes mellitus | LADA | Type 2 diabetes mellitus | |
|---|---|---|---|---|
| ECL-GADA+ | ECL-GADA− | |||
| Subjects no. of sera | 95 | 88 | 53 | 99 |
| Gender, male:female | 55:40 | 45:43 | 32:21 | 59:40 |
| Age at onset, yr | 28.90±15.81 | 45.57±14.17a | 46.69±13.71a | 43.64±12.97a |
| BMI, kg/m2 | 21.50±5.88 | 21.22±3.05 | 23.74±3.99a,b | 24.28±3.23a,b |
| Fasting C-peptide, nmol/L | 0.10±0.15 | 0.28±0.32a | 0.41±0.26a,b | 0.42±0.32a,b |
| Fasting blood glucose, mmol/L | 13.49±7.93 | 8.70±3.84a | 8.03±3.26a | 13.10±5.21b,c |
| 2-hr Postprandial C-peptide, nmol/L | 0.24±0.39 | 0.58±0.49a | 0.92±0.54a,b | 0.93±0.49a,b,c |
| 2-hr Postprandial blood glucose, mmol/L | 19.89±2.93 | 17.30±7.42 | 15.55±6.58a | 17.87±3.94 |
| HbA1c, % | 10.38±3.33 | 9.87±3.15 | 9.43±2.93 | 11.02±2.87b,c |
| AITD | 8 (8.42) | 4 (4.54) | 4 (7.54) | 0 |
| CD | 14 (14.73) | 3 (3.41) | 3 (5.66) | 0 |
Values are presented as mean±standard deviation or number (%).
LADA, latent autoimmune diabetes in adult; ECL-GADA, electrochemiluminescence-glutamic acid decarboxylase antibody; BMI, body mass index; HbA1c, glycosylated hemoglobin; AITD, autoimmune thyroid disease; CD, Celiac disease.
aP<0.05 compared to type 1 diabetes mellitus, bP<0.05 compared to ECL-GADA+, cP<0.05 compared to ECL-GADA−.