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Antifungal susceptibility and point mutations in drug targets in Candida auris. (a) Phylogenetic tree detailing clade, susceptibility to fluconazole (FCZ), amphotericin B (AMB), and micafungin (MCF), and point mutations in lanosterol 14-alpha-demethylase ERG11 (Y132F, K143R, and F126L) and beta-1,3-d-glucan synthase FKS1 (S639Y/P/F) associated with resistance. (b) Bar plot describing frequency (as a percentage) (y axis) of Y132F, K143R, and F126L point mutations in ERG11 for each clade.
