Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Apr 22;11:741. doi: 10.3389/fimmu.2020.00741

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Junqueira-Kipnis, Trentini, Marques Neto and Kipnis.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

NK cell depletion impairs protection generated by mc²-CMX or BCG vaccination. C57BL/6 mice (N = 5) depleted or not were immunized with saline, BCG (10⁷ CFU/mL), mc² (10⁸ CFU/mL), or mc²-CMX (10⁸ CFU/mL). Fifteen days after the last vaccination with mc²-CMX, animals were challenged with M. tuberculosis and 30 days after challenge, lungs were collected, processed, homogenized and plated to determine the bacillary load. (A–C) dilutions 1/100, 1/1,000, and 1/10,000 were plated and cultured for 28 days. (D) Bacillary load in the lungs of infected mice. *Statistical difference between not depleted groups.